Parkinson’s disease is a neurodegenerative disorder that
affects an individual’s speech and motor functions, they usually suffer from
tremors, the stiffness of muscles and the slowness of muscles, it is ultimately
the breakdown of the nervous system over a period of time. Individuals develop Parkinson’s
because of the loss of the neurotransmitter dopamine in the brain, the axons
containing the dopamine start in a part of the mid brain which is known as the
Substantia Niagra and they then travel to part of the forebrain called the Striatum.
A psychologist named David Parkinson (1817)
found that the pathway in the Substantia Niagra is connected to the Striatum, the
nigro-striatal pathway then degenerates which leads to Parkinson’s symptoms. L
Dopa is a drug that is used to alleviate the symptoms of Parkinson’s as there
is no cure as of yet, it is known as a DA agonist meaning that it produces more
dopamine in the brain and helps maintain the production of it.