Once a mind is tainted with overconfidence and avarice, there is no turning back. William Shakespeare’s play, Macbeth, is a tragedy that depicted how the protagonist, Macbeth, changes from being glorified as a hero to becoming a murderer that feeds off of greed and power. The two biggest causes of Macbeth’s downfall were Lady Macbeth’s manipulative actions, as well as Macbeth’s presumptuous behavior.Lady Macbeth manipulates Macbeth into performing inhumane actions. She is the primary cause of King Duncan’s death because of the fact that she forced Macbeth into committing a crime against his will. Lady Macbeth lures Macbeth: “Such I account thy love. Art thou afeard To be the same in thine own act and valor As thou art in desire?” (1.7 43-45) because Macbeth had a change of heart and suddenly refuses to kill Duncan. Lady Macbeth provokes him by questioning if his change of heart will also happen to their love. She also presumes that Macbeth is afraid to achieve the desire he’s been longing for, to be king. By demoralizing Macbeth and threatening him with the thought of being left, she convinces him to commit the deed of killing Duncan. After Duncan was killed, Macbeth showed signs of guilt by not being able to say “Amen” and wished he could unsee the blood in his hands. Lady Macbeth eases him by saying that “A little water clears us of this deed” (2.2 86). She convinces Macbeth that the sinful deed can be cleared up just by washing their hands with water, in order for them to look transparent and innocent. Lady Macbeth pushed her husband into his breaking point by persuading him with thoughts of gaining power, which made him ruthless and egotistical leading up to his very own downfall. Macbeth made rash decisions without realizing the consequences that could possibly occur. For example, he allowed himself to be manipulated by his wife, instead of following his intuitions of not killing Duncan. After his ego has been elevated, he further goes on and makes decisions without his wife and killed whoever stood a threat to his desire of gaining more power. Macbeth states, “Be innocent of the knowledge, dearest chuck, Till thou applaud the deed” (3.3 51-52). In addition, he strongly believed in the Witches’ prophecies which provided him the consolation of not being defeated, but in the end it backfired on him for relying solely on it too much. The messenger warned Macbeth: “As I did stand my watch upon the hill, I looked toward Birnam, and anon methought, The wood began to move” (5.5 41-43). Based on the second apparition, it stated that Macbeth will not be defeated until the trees of the forest move towards his castle, in which Malcolm’s army did ascend to Macbeth’s castle. It is apparent that Macbeth became too trusting when it came to him gaining power in return. This made him a simple target to manipulate, knowing that his thirst for power and title is what drives him. Overall, Macbeth’s destruction was merely caused by himself due to his poor decision making and oppressive behavior. The influence of Lady Macbeth played a role in Macbeth’s downfall. However, it was Macbeth himself who the committed deeds that were only for himself. He believed others too quickly, thus, making him the ultimate blame for his own collapse. The play, Macbeth by William Shakespeare, portrays a significant transformation of Macbeth, from a noble and courageous thane to a corrupted tyrant. The mind can be tainted, but the essence of heart can still remain. Although, it is the choice of the individual, whether or not he/she wants to be pure or be consumed by evil.