1.5.Malaria vaccination

· Chloroquine

· Quinine

· Artemisinin combination

1.6.Treatment

Malaria is treated with antimalarial treatments; the ones used depends on the type and strictness of the disease. While medications against fever are commonly used, their effects on outcomes are not clear.Severe and complicated malaria are almost always caused by infection with P. falciparum. The other species usually cause only pyretic disease. Severe and complicated malaria are medical crises since mortality rates are high (10% to 50%). Cerebral malaria is the form of severe and complicated malaria with the worst nervous symptoms. Recommended treatment for severe malaria is the arterial use of antimalarial medicines. For severe malaria, parenteral artesunate was superior to quinine in both childrenand adults. In another systematic review, artemisinin derivatives (artemether and arteether) were as effective as quinine in the treatment of cerebral malaria in children.Treatment of severe malaria involves supportive measures that are best done in a serious care unit.

Simple or uncomplicated malaria may be treated with verbalized medications. The most effective treatment for P. falciparum infection is the use of artemisinins in combination with other antimalarials (known as artemisinin-combination therapy, or ACT), which declines resistance to any single drug component.

1.7.Epidemic Disease

Anepidemic is the instantaneous spread of infection to a large number of people in an assumed population within a spell of time, generally two weeks or less. For example, in meningococcal infections an attack ratein excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic.

v Plague.

v Malaria.

v Yellow Fever.

v Blood borne diseases.

v Dengue Fever.

v Influenza, Cold and Measles diseases.

v Small pox and Polio diseases.

v Bubonic plague.

v Typhus.

v Relapsing Fever.

v Hand, Foot and Mouth disease.

1.8.Endemic Disease

A characteristic of a specific population, environment, or area. Examples ofendemic diseases include Chicken pox that follows at an expectable rate among young school children in the United States and Malaria in some regions of Africa.

1.9.Mathematical Modeling

The mathematical modeling may be defined as the following features are under given as

v Organize the problem to be examined.

v Regulate the key features.

v Signify those factors and their interface as in a mathematical way and assess the mathematical associations.

v Understand the mathematical consequences in the situation of the real-world miracle.

v Estimate how relevant the results are to the real-world situation.

If necessary re-examine the features that were considered and structure of the initial model